Annual Reviews was founded in 1932 as a nonprofit scientific publisher to help scientists cope with the ever-increasing volume of scientific research. Comprehensive, authoritative, and critical reviews written by the world's leading scientists are now published in twenty-six disciplines in the biological, physical, and social sciences. According to the "Impact Factor" rankings of the Institute for Scientific Information's Science Citation Index, each Annual Review ranks at or near the top of its respective subject category. A searchable title and author database and a collection of abstracts may be found at https://www.annualreviews.org//. The web site also provides information and pricing for all printed volumes, online publications, and reprint collections.