Infection Control and Hospital Epidemiology Publication Info
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An Outbreak of Hospital‐Acquired Hepatitis B Virus Infection Among Patients Receiving Chronic Hemodialysis
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Abstract(back to top)
OBJECTIVE. To investigate a cluster of hepatitis B virus (HBV) infections between December 1995 and May 1996 among chronic hemodialysis patients in one county.
SETTING. Two dialysis centers (A and B) and a hospital (C) in one county.
PATIENTS. Six case‐patients who were dialyzed in one of two centers, A and B, and had all been hospitalized between January and February 1996 at hospital C.
METHODS. Patient 1, usually dialyzed in center A, seroconverted to hepatitis B surface antigen (HBsAg) in December 1995 and could have been the source of infection for the others, who seroconverted between March and April 1996. Two cohort studies were conducted: one among patients dialyzed in center A, to determine where transmission had occurred, and one among patients dialyzed at hospital C at the time patient 1 was hospitalized, to identify factors associated with infection.
RESULTS. Four (15%) of the 26 susceptible patients dialyzed at center A became infected with HBV. Hospitalization at hospital C when patient 1 was hospitalized was associated with infection (P=.002). A cohort study of the 10 susceptible patients dialyzed at hospital C during the time patient 1 was hospitalized did not identify specific risk factors for infection. However, supplies and multidose vials were shared routinely among patients, providing opportunities for transmission.
CONCLUSION. When chronic hemodialysis patients require dialysis while hospitalized, their HBsAg status should be reviewed, and no instrument, supplies, or medications should be shared among them.
Bibliographic Information(back to top)
- An Outbreak of Hospital‐Acquired Hepatitis B Virus Infection Among Patients Receiving Chronic Hemodialysis
- Yvan J.F. Hutin , MD, MSc, Susan T. Goldstein , MD, Jay K. Varma , MD, Joan B. O’Dair , RN, MPH, Eric E. Mast , MD, MPH, Craig N. Shapiro , MD and Miriam J. Alter , PhD
- Infection Control and Hospital Epidemiology
- Vol. 20, No. 11 (November 1999) (pp. 731-735)
Notes and References(back to top)
This item contains 1 note(s).
Notes
From the Hepatitis Branch (Drs. Hutin, Goldstein, Mast, Shapiro, and Alter), Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases; Epidemic Intelligence Service (Dr. Hutin), Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia; and the Department of Internal Medicine (Dr. Varma), University of California, San Diego, California; and the Allegheny County Department of Public Health (Ms. O’Dair), Pittsburgh, Pennsylvania.Address reprint requests to Miriam J. Alter, PhD, Centers for Disease Control and Prevention, MS G37, 1600 Clifton Rd, Atlanta, GA 30333.Results of this study were presented as an oral presentation at the Seventh Annual Meeting of the Society for Healthcare Epidemiology of America, St Louis, Missouri, April 27‐29, 1997. At the time of the investigation, Dr. Varma was a medical student assigned to the Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia. The authors thank the Allegheny County Health Department; the healthcare professionals who provide dialysis services in centers A and B and in hospital C; the infection control unit in hospital C; and Matthew Arduino, DrPH, and Jerome Tokars, MD, Hospital Infection Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention.99‐OA‐058. Hutin YJF, Goldstein ST, Varma JK, O’Dair JB, Mast EE, Shapiro CN, Alter MJ. An outbreak of hospital‐acquired hepatitis B virus infection among patients receiving chronic hemodialysis. Infect Control Hosp Epidemiol 1999;20:731‐735.
Items Citing this Item (back to top)
2 item(s) in JSTOR cite this item
- Taraz Samandari , MD, PhD; Naile Malakmadze , MD; Sharon Balter , MD; Joseph F. Perz , DrPH; Marina Khristova , PhD; Leah Swetnam , MD; Katherine Bornschlegel , MPH; Michael S. Phillips , MD; Iqbal A. Poshni , PhD; Preeti Nautiyal , MD; Omana V. Nainan , PhD; Beth P. Bell , MD, MPH; Ian T. Williams , PhDVol. 26, No. 9 (September 2005) pp. 745-750Stable URL: http://www.jstor.org/stable/10.1086/502612
- Gérard Krause , MD, DrMed; Mary Jo Trepka , MD, MPH; Robert S. Whisenhunt; Dolly Katz , PhD; Omana Nainan , PhD; Steven T. Wiersma , MD, MPH; Richard S. Hopkins , MD, MScVol. 24, No. 2 (February 2003) pp. 122-127Stable URL: http://www.jstor.org/stable/10.1086/502176