You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:


Log in to your personal account or through your institution.

Factors Associated With Tuberculin Reactivity in Two General Hospitals in Mexico

María de Lourdes García‐García , MD, DrSc, Aida Jiménez‐Corona , MD, MSc, María Eugenia Jiménez‐Corona , MD, Leticia Ferreyra‐Reyes , MD, Kenneth Martínez , MSEE, CIH, Blanca Rivera‐Chavira , PhD, María Elena Martínez‐Tapia , MD, Emilio Valenzuela‐Miramontes , MD, Manuel Palacios‐Martínez , MD, Luis Juárez‐Sandino , MD and José Luis Valdespino‐Gómez , MD, MPH
Infection Control and Hospital Epidemiology
Vol. 22, No. 2 (February 2001), pp. 88-93
DOI: 10.1086/501869
Stable URL:
Page Count: 6
  • Subscribe ($19.50)
  • Cite this Item
Item Type
Factors Associated With Tuberculin Reactivity in Two General Hospitals in Mexico
Preview not available


OBJECTIVE.  To identify risk factors associated with tuberculin reactivity in healthcare workers (HCWs). DESIGN.  Cross‐sectional survey of tuberculin reactivity (2 TU of purified protein derivative (PPD) RT23, using the Mantoux two‐step test). SETTING.  Two general hospitals located in a region with a high prevalence of tuberculosis and high bacille Calmette‐Guérin (BCG) coverage. PARTICIPANTS.  Volunteer sample of HCWs. RESULTS.  605 HCWs were recruited: 71.2% female; mean age, 36.4 (standard deviation [SD], 8.2) years; 48.9% nurses, 10.4% physicians, 26.8% administrative personnel; mean time of employment, 10.9 (SD, 6.7) years. PPD reactivity (>10 mm) was found in 390 (64.5%). Multivariate analysis revealed an association of tuberculin reactivity with occupational exposure in the hospital: participation in autopsies (odds ratio [OR], 9.3; 95% confidence interval [CI95], 2.1‐40.5; P=.003.), more than 1 year of employment (OR, 2.4; CI95, 1.1‐5.0; P=.02), work in the emergency or radiology departments (OR, 2.0; CI95, 1.03‐3.81; P=.04), being physicians or nurses (OR, 1.5; CI95, 1.04‐2.11; P=.03), age (OR, 1.04; CI95, 1.02‐1.07 per year of age; P<.001), and BCG scar (OR, 2.1; CI95, 1.2‐3.4; P=.005). CONCLUSIONS.  Although the studied population has a high baseline prevalence of tuberculosis infection and high coverage of BCG vaccination, nosocomial risk factors associated with PPD reactivity were identified as professional risks; strict early preventive measures must be implemented accordingly.

Page Thumbnails