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Isoniazid‐Resistant Cavitary Tuberculosis in a Physician Following Isoniazid Prophylaxis
Tobi B. Karchmer , MD, MS, John D. Phipps , MD, Eve T. Giannetta , RN and Barry M. Farr , MD, MSc
Infection Control and Hospital Epidemiology
Vol. 23, No. 10 (October 2002), pp. 622-625
Published by: Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America
Stable URL: http://www.jstor.org/stable/10.1086/501983
Page Count: 4
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ABSTRACT Single‐drug prophylaxis is recommended after tuberculin skin test conversion, but not when there is active disease on chest radiograph because resistance develops frequently. Isoniazid‐resistant tuberculosis developed in a physician receiving prophylaxis despite “faint left upper lobe soft tissue density” on chest radiograph. Ignoring active disease on chest x‐ray renders this strategy counterproductive and cost ineffective.
© 2002 by The Society for Healthcare Epidemiology of America. All rights reserved.