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Transmission of Drug‐Resistant HIV After an Occupational Exposure Despite Postexposure Prophylaxis With a Combination Drug Regimen

Elise M. Beltrami , MD, Chi‐Cheng Luo , PhD, Nicolas de la Torre , BS and Denise M. Cardo , MD
Infection Control and Hospital Epidemiology
Vol. 23, No. 6 (June 2002), pp. 345-348
DOI: 10.1086/502065
Stable URL: http://www.jstor.org/stable/10.1086/502065
Page Count: 4
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Transmission of Drug‐Resistant HIV After an Occupational Exposure Despite Postexposure Prophylaxis With a Combination Drug Regimen
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Abstract

ABSTRACT We documented a case of occupational human immunodeficiency virus (HIV) despite postexposure prophylaxis (PEP) with a combination drug regimen after percutaneous injury with a needle from a sharps disposal container in the hospital room of an HIV‐infected patient. This failure of PEP with a combination drug regimen may have been related to antiretroviral drug resistance, other factors, or both. This case highlights the importance of preventing injury to prevent occupational transmission of HIV.

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