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Journal Article

Registration of Disinfectants Based on Relative Microbicidal Activity

William A. Rutala , PhD, MPH and David J. Weber , MD, MPH
Infection Control and Hospital Epidemiology
Vol. 25, No. 4 (April 2004), pp. 333-341
DOI: 10.1086/502401
Stable URL:
Page Count: 9
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Registration of Disinfectants Based on Relative Microbicidal Activity
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EXCERPT Along with proper hand hygiene, disinfection of contaminated surfaces and medical instruments has been a key method of preventing patient‐to‐environment‐to‐patient transmission of infectious agents via the hands of healthcare workers.1‐3 However, there is growing concern regarding the increase in antibiotic‐resistant pathogens for which environmental and device contamination may play a role in disease transmission, such as methicillin‐resistant Staphylococcus aureus (MRSA), vancomycin‐resistant Enterococcus (VRE), Clostridium difficile, and multidrugresistant aerobic gram‐negative bacilli (eg, Pseudomonas aeruginosa and Acinetobacter).1 Proper use of disinfectants plays an important role in reducing person‐to‐person transmission of these pathogens.

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