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Risk of Clostridium difficile–Associated Disease Among Patients Receiving Proton‐Pump Inhibitors in a Quebec Medical Intensive Care Unit

Mathieu Beaulieu , MSc, MBA, David Williamson  MSc, BCPS, Gilbert Pichette , MD, FRCP and Jean Lachaine , PhD
Infection Control and Hospital Epidemiology
Vol. 28, No. 11 (November 2007), pp. 1305-1307
DOI: 10.1086/521664
Stable URL: http://www.jstor.org/stable/10.1086/521664
Page Count: 3
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Risk of Clostridium difficile–Associated Disease Among Patients Receiving Proton‐Pump Inhibitors in a Quebec Medical Intensive Care Unit
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Abstract

Our study was conducted to determine whether use of gastric acid–suppressive agents increased the risk of Clostridium difficile–associated disease (CDAD) in a medical intensive care unit of one of the first hospitals to be threatened by the current CDAD epidemic in Quebec, Canada. Our findings suggest that efforts to determine risk factors for CDAD should focus on other areas, such as older age and antibiotic use.

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