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Constructing Unit-Specific Empiric Treatment Guidelines for Catheter-Related and Primary Bacteremia by Determining the Likelihood of Inadequate Therapy

Megan E. Davis PharmDBCPS, Deverick J. Anderson MDMPH, Michelle Sharpe PharmD, Luke F. Chen MBBSMPH, FRACP and Richard H. Drew PharmDMS, BCPS, FCCP
Infection Control and Hospital Epidemiology
Vol. 33, No. 4, Special Topic Issue: Antimicrobial Stewardship (April 2012), pp. 416-420
DOI: 10.1086/664756
Stable URL: http://www.jstor.org/stable/10.1086/664756
Page Count: 5
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Constructing Unit-Specific Empiric Treatment Guidelines for Catheter-Related and Primary Bacteremia by Determining the Likelihood of Inadequate Therapy
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Abstract

This study aimed to determine the feasibility of using likelihood of inadequate therapy (LIT), a parameter calculated by using pathogen frequency and in vitro susceptibility for determination of appropriate empiric antibiotic therapy for primary bloodstream infections. Our study demonstrates that LIT may reveal differences in traditional antibiograms.

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