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A Nonproducer T Lymphoblastoid Cell Line from Marek's Disease Transplantable Tumor (JMV)

K. Nazerian, E. Ann Stephens, J. M. Sharma, Lucy F. Lee, Maiga Gailitis and R. L. Witter
Avian Diseases
Vol. 21, No. 1 (Jan. - Mar., 1977), pp. 69-76
DOI: 10.2307/1589365
Stable URL: http://www.jstor.org/stable/1589365
Page Count: 8
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
A Nonproducer T Lymphoblastoid Cell Line from Marek's Disease Transplantable Tumor (JMV)
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Abstract

A continuous lymphoblastoid cell line was established from a JMV tumor transplant related to Marek's disease (MD). It is designated RPL-1 (JMV) lymphoblastoid cell line. This cell line contains DNA sequences complementary to MD virus DNA and has an antigen similar to MD-tumor-associated surface antigen (MATSA). However, it lacks any MD virus (MDV) rescuable in vivo or in vitro. The cell line has surface antigens typical of chicken thymus cells (T cells) and histocompatability antigens different from those of the host chicken.

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