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Anticoccidial Efficacy of Diclazuril in Broilers under Simulated Natural Conditions in Floor Pens

Larry R. McDougald, Barbara P. Seibert, Greg F. Mathis and Carey L. Quarles
Avian Diseases
Vol. 34, No. 4 (Oct. - Dec., 1990), pp. 905-910
DOI: 10.2307/1591381
Stable URL: http://www.jstor.org/stable/1591381
Page Count: 6
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Anticoccidial Efficacy of Diclazuril in Broilers under Simulated Natural Conditions in Floor Pens
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Abstract

Anticoccidial efficacy of diclazuril given for 42 to 49 days of age was evaluated in broiler chickens. Mortality from coccidiosis in unmedicated controls averaged 12.90% for six experiments. Treatment with diclazuril at 0.5, 1.0, and 1.5 ppm reduced coccidiosis mortality to 1.41%, 0.85%, or 0.63%, respectively, and reduced average total lesion scores by 78%, 81% or 82%, respectively. The final live weight and feed conversion at 49 days of age was significantly improved by treatment with diclazuril at all levels. Comparisons in some trials suggested that 1.0 ppm of diclazuril was equal or superior to the other anticoccidial drugs. There was no evidence that diclazuril harmed performance, even when given at 1.5 ppm. /// Se evaluó la efectividad anticoccidiana del diclazuril administrado durante 42 días en pollos de engorde sacrificados a los 49 días de edad. La mortalidad por coccidiosis en los controles no medicados fue de 12.9% en los seis experimentos. El tratamiento con diclazuril a razón de 0.5, 1.0 o 1.5 ppm, redujo la mortalidad por coccidiosis a 1.41%, 0.85% o 0.63%, respectivamente, y redujo el promedio total de lesiones en un 78%, 81% u 82%, respectivamente. El peso vivo final y la conversión alimenticia a los 49 días de edad se incrementó significantemente por el tratamiento con diclazuril en todos los niveles. Las comparaciones en algunas de las pruebas sugirieron que 1.0 ppm de diclazuril resultó igual o superior a otros fármacos anticoccidianos bajo condiciones prácticas. No hubo evidencia de que el diclazuril afectó negativamente el rendimiento, aún cuando fue administrado a una concentración de 1.5 ppm.

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