Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If You Use a Screen Reader

This content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.

Astrovirus Infection in Hatchling Turkeys: Histologic, Morphometric, and Ultrastructural Findings

Mari L. Thouvenelle, Joseph S. Haynes and Don L. Reynolds
Avian Diseases
Vol. 39, No. 2 (Apr. - Jun., 1995), pp. 328-336
DOI: 10.2307/1591875
Stable URL: http://www.jstor.org/stable/1591875
Page Count: 9
  • Read Online (Free)
  • Download ($12.00)
  • Subscribe ($19.50)
  • Cite this Item
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Astrovirus Infection in Hatchling Turkeys: Histologic, Morphometric, and Ultrastructural Findings
Preview not available

Abstract

In three separate experiments, 2- or 5-day-old commercial turkey poults were inoculated orally with astrovirus and examined for clinical signs and for gross and microscopic lesions over a period of 14 days. By day 2 postinoculation (PI), inoculated poults had developed diarrhea, generalized loss of intestinal tone, and dilated ceca that contained light-yellow fluid feces and gas; these changes persisted through day 10 PI. Mild crypt hyperplasia was the only change discernible by light microscopy, and it was first noted in the proximal jejunum on day 1 PI, in the distal jejunum and ileum on day 3 PI, and in the duodenum on day 5 PI. A significant (P < 0.05) increase in crypt depth and area was documented by image analysis on day 3 PI. Ultrastructural evaluation revealed intracytoplasmic aggregates of astrovirus in enterocytes on the sides and base of villi in the ileum and distal jejunum on day 3 PI. Based on the findings, it was concluded that astrovirus caused lesions and replicated in both upper and lower segments of the small intestine in turkey poults. /// En tres experimentos separados, se inocularon oralmente pavitos de dos o cinco días de edad con astrovirus y se examinaron para observar la presencia de signos clínicos y lesiones macro y microscópicas durante un periodo de 14 días. Dos días después de la inoculación, los pavitos inoculados mostraron diarrea, pérdida generalizada de tono intestinal y ciegos dilatados que contenían heces líquidas amarillentas con presencia de gas. Estas lesiones se observaron durante 10 días. La única lesión encontrada al microscopio fue una leve hiperplasia de las criptas, observada primero en el yeyuno proximal un día después de la inoculación, en el yeyuno distal e íleo al tercer día después de la inoculación, y en el duodeno al quinto día. Se observó un aumento significante (P < 0.05) en la profundidad y en el área de las criptas al tercer día después de la inoculación. La evaluación ultraestructural reveló agregados de astrovirus intracitoplasmáticos en los enterocitos, a los lados y en la base de la vellosidad del íleo y en el yeyuno distal al tercer día después de la inoculación. Basados en estos resultados, los astrovirus causaron lesiones y se replicaron en la parte superior e inferior del intestino delgados de los pavitos.

Page Thumbnails

  • Thumbnail: Page 
328
    328
  • Thumbnail: Page 
329
    329
  • Thumbnail: Page 
330
    330
  • Thumbnail: Page 
331
    331
  • Thumbnail: Page 
332
    332
  • Thumbnail: Page 
333
    333
  • Thumbnail: Page 
[334]
    [334]
  • Thumbnail: Page 
335
    335
  • Thumbnail: Page 
336
    336