Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If You Use a Screen Reader

This content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.

Effect of Spectinomycin on Escherichia coli Infection in 1-Day-Old Ducklings

Marisue Freed, John P. Clarke, T. L. Bowersock, W. G. Van Alstine, Janice M. Balog and Patricia Y. Hester
Avian Diseases
Vol. 37, No. 3 (Jul. - Sep., 1993), pp. 763-766
DOI: 10.2307/1592026
Stable URL: http://www.jstor.org/stable/1592026
Page Count: 4
  • Read Online (Free)
  • Download ($12.00)
  • Subscribe ($19.50)
  • Cite this Item
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Effect of Spectinomycin on Escherichia coli Infection in 1-Day-Old Ducklings
Preview not available

Abstract

Two challenge trials and one confirmation trial were conducted to evaluate the efficacy of spectinomycin in the treatment of 1-day-old ducklings infected with Escherichia coli. In the challenge trials, ducklings were injected in the right posterior thoracic air sac with 0.2 cm3 of broth containing 108 colony-forming units E. coli (strain O78, E38)/ml. Spectinomycin at dosage levels of 2.5 mg, 5.0 mg, and 10.0 mg of activity was injected subcutaneously 6 hours following infection. The confirmation trial was conducted to confirm the challenge trials; procedures were similar to those used in the challenge trials, except that only the 5.0 mg of activity dosage of spectinomycin was used. In both types of trials, spectinomycin-treated ducklings had significantly lower mortality and higher average weight gain, average daily gain, and feed consumption than infected unmedicated controls. These results indicate that spectinomycin is effective in treating ducks for experimentally induced coli-bacillosis caused by E. coli (strain O78, E38). /// Se realizaron dos experimentos de desafío y un tercero de confirmación para evaluar la eficacia de la espectinomicina en el tratamiento de la infección por Escherichia coli en paticos de un día de edad. En los experimentos de desafío, los paticos fueron inyectados en el saco aéreo torácico posterior derecho con 0.2 ml de caldo que contenía 108 unidades formadoras de colonias/ml de las cepas E. coli O78 y E38. Se inyectó espectinomicina subcutáneamente a dosis de 2.5 mg, 5.0 mg y 10.0 mg de actividad 6 horas después de la infección. El experimento de confirmación fue realizado para verificar los resultados obtenidos en los experimentos de desafío. Los procedimientos fueron similares al utilizado en los experimentos de desafío excepto que se usó únicamente una dosis activa de 5.0 mg de espectinomicina. En ambos tipos de experimentos, la espectinomicina redujo significantemente la mortalidad e incrementó el promedio de la ganancia de peso, el promedio de la ganancia diaria y el consumo de alimento cuando se compararon con los controles no medicados. Estos resultados indican que la espectinomicina fue efectiva en el tratamiento de la colibacilosis inducida experimentalmente con las cepas O78 y E38 de E. coli en paticos.

Page Thumbnails

  • Thumbnail: Page 
763
    763
  • Thumbnail: Page 
764
    764
  • Thumbnail: Page 
765
    765
  • Thumbnail: Page 
766
    766