Access

You are not currently logged in.

Access JSTOR through your library or other institution:

login

Log in through your institution.

Journal Article

Red Blood Cells: Their Dual Role in Thrombus Formation

V.T. Turitto and H.J. Weiss
Science
New Series, Vol. 207, No. 4430 (Feb. 1, 1980), pp. 541-543
Stable URL: http://www.jstor.org/stable/1684039
Page Count: 3

You can always find the topics here!

Topics: Platelets, Blood, Hematocrit, Thrombosis, Reactivity, Erythrocytes, Viruses, Gels, Virology, Blood plasma
Were these topics helpful?
See something inaccurate? Let us know!

Select the topics that are inaccurate.

Cancel
  • More info
  • Add to My Lists
  • Cite this Item
Preview not available
Preview not available

Abstract

Red blood cells may have a physical and chemical effect on the interaction between platelets and blood vessel surfaces. Under flow conditions in which primarily physical effects prevail, platelet adhesion increases fivefold as hematocrit values increase from 10 to 40 percent but undergoes no further increase from 40 to 70 percent, implying a saturation of the transport-enhancing capabilities of red cells. For flow conditions in which platelet-surface reactivity is more dominant, platelet adhesion and thrombus formation increase monotonically as hematocrit values increase from 10 to 70 percent. Thus red cells may have a significant influence on hemostasis and thrombosis; the nature of the effect is apparently related to the flow conditions.

Page Thumbnails

  • Thumbnail: Page 
541
    541
  • Thumbnail: Page 
542
    542
  • Thumbnail: Page 
543
    543