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Plasminogen is Synthesized by Primary Cultures of Rat Hepatocytes

John F. Bohmfalk and Gerald M. Fuller
Science
New Series, Vol. 209, No. 4454 (Jul. 18, 1980), pp. 408-410
Stable URL: http://www.jstor.org/stable/1684775
Page Count: 3
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Plasminogen is Synthesized by Primary Cultures of Rat Hepatocytes
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Abstract

The accumulation of rat plasminogen in the medium of primary monolayer cultures of adult parenchymal hepatocytes was detected with a quantitative immunological assay. These primary cultures synthesized and secreted both circulating isozymic forms of plasminogen at rates sufficient to account for the majority of the in vivo plasminogen turnover.

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