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Plasminogen is Synthesized by Primary Cultures of Rat Hepatocytes
John F. Bohmfalk and Gerald M. Fuller
New Series, Vol. 209, No. 4454 (Jul. 18, 1980), pp. 408-410
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1684775
Page Count: 3
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The accumulation of rat plasminogen in the medium of primary monolayer cultures of adult parenchymal hepatocytes was detected with a quantitative immunological assay. These primary cultures synthesized and secreted both circulating isozymic forms of plasminogen at rates sufficient to account for the majority of the in vivo plasminogen turnover.
Science © 1980 American Association for the Advancement of Science