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Mycoplasma pneumoniae Infection: Role of a Surface Protein in the Attachment Organelle

P. C. Hu, R. M. Cole, Y. S. Huang, J. A. Graham, D. E. Gardner, A. M. Collier and W. A. Clyde
Science
New Series, Vol. 216, No. 4543 (Apr. 16, 1982), pp. 313-315
Stable URL: http://www.jstor.org/stable/1687738
Page Count: 3
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Abstract

Attachment of Mycoplasma pneumoniae to host cells by means of a specialized terminus initiates infection. Monoclonal antibodies to a surface protein (P1) inhibit this process, and react with a region of the tip covered with peplomer-like particles. Since antibodies against the P1 protein are generated by natural and experimental infection and by immunization, the substance may be an important determinant of protective immunity.

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