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On the Reported Inhibition of Monoamine Oxidase by an Agent with Sedative Properties

Sydney Spector, Parkhurst A. Shore and Bernard B. Brodie
Science
New Series, Vol. 132, No. 3429 (Sep. 16, 1960), p. 735
Stable URL: http://www.jstor.org/stable/1705803
Page Count: 1
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Abstract

1-Benzyl-2-methyl-5-methoxy-tryptamine has been reported, on the basis of indirect evidence, to inhibit monoamine oxidase. More direct experiments, however, demonstrate that the drug is devoid of the ability to block monoamine oxidase in brain in vitro or in vivo.

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