Access

You are not currently logged in.

Access JSTOR through your library or other institution:

login

Log in through your institution.

Journal Article

Autoimmune Response in Rabbits Injected with Rat and Rabbit Liver Ribosomes

Matthew C. Dodd, Nancy J. Bigley, Virginia B. Geyer, Francis W. McCoy and Henry E. Wilson
Science
New Series, Vol. 137, No. 3531 (Aug. 31, 1962), pp. 688-689
Stable URL: http://www.jstor.org/stable/1709807
Page Count: 2

You can always find the topics here!

Topics: Ribosomes, Liver, Pathology, Antibodies, Autoantibodies, Antigens, Erythrocytes, Globulins, Leukopenia, Leukocytes
  • More info
  • Add to My Lists
  • Cite this Item
Preview not available
Preview not available

Abstract

Autoimmune hemolytic anemia and leukopenia, circulating autoantibodies for erythrocytes, leukocytes, and ribosomes; pathological changes in liver, spleen, heart, brain, and kidneys were produced in rabbits injected with rat or rabbit liver ribosomes. The hematologic and pathologic changes were reproduced by injection of anti-ribosomal serum into normal rabbits. The autoantibody specificity was related primarily to nucleotides and nucleosides.

Page Thumbnails

  • Thumbnail: Page 
688
    688
  • Thumbnail: Page 
689
    689