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Intracellular Potentials of Cortical Neurons during Focal Epileptogenic Discharges
Eli S. Goldensohn and Dominick P. Purpura
New Series, Vol. 139, No. 3557 (Mar. 1, 1963), pp. 840-842
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1710496
Page Count: 3
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Focal electroencephalographic discharges in lesions of cortex induced by freezing are associated with prolonged membrane depolarizations and hyperpolarizations in neurons located at various depths in the lesion sites. Transmembrane potential changes have properties similar to those of postsynaptic potentials. The temporal relationship between intracellular potentials and paroxysmal discharges indicates that the latter are extracellularly recorded summations of synchronously developing depolarizations and hyperpolarizations in complex synaptic organizations of neurons.
Science © 1963 American Association for the Advancement of Science