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Inhibition of Growth of Chick Embryo by Inhibition of Deoxycytidylate Deaminase

Jay S. Roth, G. Buccino and N. W. Klein
Science
New Series, Vol. 142, No. 3598 (Dec. 13, 1963), pp. 1473-1474
Stable URL: http://www.jstor.org/stable/1712005
Page Count: 2
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Abstract

Deoxyguanylate when added to chick embryos grown in explant inhibited growth and development. Deoxycytidylate deaminase activity was inhibited both in the explants and in vitro; since the effect was quite specific, it is suggested that this may represent another control mechanism for deoxynucleotide synthesis.

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