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Submaxillary Gland of Mouse: Effects of a Fraction on Tissues of Mesodermal Origin in vitro
D. Gandini Attardi, R. Levi-Montalcini, B. S. Wenger and P. U. Angeletti
New Series, Vol. 150, No. 3701 (Dec. 3, 1965), pp. 1307-1309
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1717655
Page Count: 3
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A macromolecular fraction from mouse salivary glands markedly enhances growth of mesenchymal tissues in vitro. The same fraction causes dedifferentiation of tissues of mesodermal origin, such as muscle and cartilage. Dedifferentiated tissues do not divide but survive in good condition, while controls in the same cultural media undergo regressive changes.
Science © 1965 American Association for the Advancement of Science