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Cytochemical Localization of Lactate Dehydrogenase in Muscular Dystrophy of the Mouse
H. D. Fahimi and P. Roy
New Series, Vol. 152, No. 3730 (Jun. 24, 1966), pp. 1761-1763
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1718380
Page Count: 3
You can always find the topics here!Topics: Phenazines, Lactates, Incubation, Fast twitch muscle fibers, Muscle fibers, Dehydrogenases, Sprains and strains, Muscular dystrophies, Biochemistry, Muscles
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By use of phenazine methosulfate and the "incubation mixture film method," lactate dehydrogenase activity has been demonstrated in the dystrophic muscle fibers of strain 129 mice. The results indicate that for demonstration of lactate dehydrogenase activity in dystrophic muscle fibers phenazine methosulfate is necessary. This finding is typical for the "white" muscle fibers in the normal muscle and suggests that the dystrophy affects primarily the "white" muscle fibers.
Science © 1966 American Association for the Advancement of Science