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Cytochemical Localization of Lactate Dehydrogenase in Muscular Dystrophy of the Mouse

H. D. Fahimi and P. Roy
Science
New Series, Vol. 152, No. 3730 (Jun. 24, 1966), pp. 1761-1763
Stable URL: http://www.jstor.org/stable/1718380
Page Count: 3
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Cytochemical Localization of Lactate Dehydrogenase in Muscular Dystrophy of the Mouse
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Abstract

By use of phenazine methosulfate and the "incubation mixture film method," lactate dehydrogenase activity has been demonstrated in the dystrophic muscle fibers of strain 129 mice. The results indicate that for demonstration of lactate dehydrogenase activity in dystrophic muscle fibers phenazine methosulfate is necessary. This finding is typical for the "white" muscle fibers in the normal muscle and suggests that the dystrophy affects primarily the "white" muscle fibers.

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