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Journal Article

Field Ion Microscopical Imaging of Biomolecules

Erwin W. Müller and Klaus D. Rendulic
Science
New Series, Vol. 156, No. 3777 (May 19, 1967), pp. 961-963
Stable URL: http://www.jstor.org/stable/1721548
Page Count: 3

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Topics: Molecules, Electric fields, Ions, Platinum, Imaging, Atoms, Plating, Evaporation, Coenzymes, Microscopes
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Field Ion Microscopical Imaging of Biomolecules
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Abstract

Specimen molecules are protected from field desorption by embedding them in a platinum matrix, with the use of electrolytic codeposition on tungsten tips. High-resolution helium ion images are obtained when the biomolecules are exposed during gradual removal of surface layers by controlled field evaporation. Structured images of individual molecules of coenzyme I and vitamin B$_{12}$ are seen.

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