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Herpes-Type Virus and Chromosome Marker in Normal Leukocytes after Growth with Irradiated Burkitt Cells

Werner Henle, Volker Diehl, Gertrude Kohn, Harald zur Hausen and Gertrude Henle
Science
New Series, Vol. 157, No. 3792 (Sep. 1, 1967), pp. 1064-1065
Stable URL: http://www.jstor.org/stable/1722232
Page Count: 2
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Abstract

Cultured cells derived from male patients with Burkitt's lymphoma and harboring herpes-type virus particles were lethally irradiated. These irradiated cells induced normal peripheral leukocytes of female infants to grow within 2 to 4 weeks after mixed cultivation. Cells of a line free of this agent failed to stimulate growth. If either type of cell was cultured separately, it did not survive under the experimental conditions. Herpes-type viral antigen and C-group chromosomal marker previously described in cultured Burkitt cells were found in all of the female cell cultures that were obtained.

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