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Journal Article

Delayed Hypersensitivity in Man: A Correlate in vitro and Transfer by an RNA Extract

Daniel E. Thor
Science
New Series, Vol. 157, No. 3796 (Sep. 29, 1967), pp. 1567-1569
Stable URL: http://www.jstor.org/stable/1722932
Page Count: 3
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Delayed Hypersensitivity in Man: A Correlate in vitro and Transfer by an RNA Extract
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Abstract

The migration of sensitized human monocytic-phagocytic cells from lymph-node tissue-culture suspensions was regularly and specifically inhibited by purified protein derivative or histoplasmin. Moreover, when nonsensitive cells were incubated with an RNA extract from lymph nodes of donors sensitive to purified protein derivative, histoplasmin, or both, the migration of these cells was specifically inhibited by these antigens. Ribonuclease inactivated the RNA extract.

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