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Delayed Hypersensitivity in Man: A Correlate in vitro and Transfer by an RNA Extract
Daniel E. Thor
New Series, Vol. 157, No. 3796 (Sep. 29, 1967), pp. 1567-1569
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1722932
Page Count: 3
You can always find the topics here!Topics: RNA, Tuberculin, Histoplasmin, Antigens, Lymphocytes, Chemical suspensions, Delayed hypersensitivity, Animal migration behavior, Lymph nodes, Capillary tubes
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The migration of sensitized human monocytic-phagocytic cells from lymph-node tissue-culture suspensions was regularly and specifically inhibited by purified protein derivative or histoplasmin. Moreover, when nonsensitive cells were incubated with an RNA extract from lymph nodes of donors sensitive to purified protein derivative, histoplasmin, or both, the migration of these cells was specifically inhibited by these antigens. Ribonuclease inactivated the RNA extract.
Science © 1967 American Association for the Advancement of Science