Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

Concanavalin A in vivo: Induction of Hemorrhagic Skin Lesions (Arthus-Like Reactions) in Mice

Leon S. Kind and Warren A. Petersen
Science
New Series, Vol. 160, No. 3825 (Apr. 19, 1968), pp. 312-313
Stable URL: http://www.jstor.org/stable/1723773
Page Count: 2
  • More info
  • Cite this Item
Preview not available
Preview not available

Abstract

Concanavalin A injected into the skin of mice induced the formation of hemorrhagic Arthus-like lesions. No lesions resulted if concanavalin A was adsorbed with insoluble $\alpha _{2}$-macroglobulin or if mice were first treated with nitrogen mustard. The ability of concanavalin A, phytohemag-glutinin, or pokeweed mitogen to induce skin lesions seemed to parallel their ability to precipitate serum proteins.

Page Thumbnails

  • Thumbnail: Page 
312
    312
  • Thumbnail: Page 
313
    313