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Activation of Hageman Factor by L-Homocystine
Oscar D. Ratnoff
New Series, Vol. 162, No. 3857 (Nov. 29, 1968), pp. 1007-1009
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1725251
Page Count: 3
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L-Homocystine activates Hageman factor, as demonstrated by its capacity to initiate clotting and to induce the evolution of plasma kinins. Perhaps, strategically located deposits of this amino acid are responsible for the unusual frequency of thrombosis in patients with homocystinuria.
Science © 1968 American Association for the Advancement of Science