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Histone Synthesis in vitro by Cytoplasmic Microsomes from HeLa Cells

Dieter Gallwitz and Gerald C. Mueller
Science
New Series, Vol. 163, No. 3873 (Mar. 21, 1969), pp. 1351-1353
Stable URL: http://www.jstor.org/stable/1726404
Page Count: 3
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Histone Synthesis in vitro by Cytoplasmic Microsomes from HeLa Cells
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Abstract

HeLa cell microsomes incorporate labeled amino acids in vitro into acid-soluble proteins which have the same electrophoretic mobility as histones isolated from the purified HeLa cell nuclei. The capacity to synthesize histones in vitro is dependent on deoxyribonucleic acid synthesis in the cells from which the microsomal fraction is prepared.

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