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Alanine: Key Role in Gluconeogenesis

Philip Felig, Thomas Pozefsky, Errol Marliss and George F. Cahill, Jr.
Science
New Series, Vol. 167, No. 3920 (Feb. 13, 1970), pp. 1003-1004
Stable URL: http://www.jstor.org/stable/1728239
Page Count: 2
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Abstract

Of 20 amino acids measured, alanine is the principal amino acid released by forearm muscle of man, in accord with its being the principal amino acid extracted by liver for gluconeogenesis. This occurs in both the postabsorptive state and after 4 to 6 weeks of starvation, when total amino acid release is markedly diminished.

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