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L-Dopa: Effect on Concentrations of Dopamine, Norepinephrine, and Serotonin in Brains of Mice

G. M. Everett and J. W. Borcherding
Science
New Series, Vol. 168, No. 3933 (May 15, 1970), pp. 849-850
Stable URL: http://www.jstor.org/stable/1729689
Page Count: 2
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Abstract

Large doses of L-dopa given to mice produced marked increases in brain dopamine, no change in norepinephrine, and a remarkable decrease in brain serotonin. This reduction apparently results from a release or displacement, or both, of serotonin from its storage sites.

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