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Homozygous Hb J Tongariki: Evidence for Only One Alpha Chain Structural Locus in Melanesians

Ruth K. Abramson, Donald L. Rucknagel, Donald C. Shreffler and Jan J. Saave
Science
New Series, Vol. 169, No. 3941 (Jul. 10, 1970), pp. 194-196
Stable URL: http://www.jstor.org/stable/1730323
Page Count: 3
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Homozygous Hb J Tongariki: Evidence for Only One Alpha Chain Structural Locus in Melanesians
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Abstract

A high frequency of Hb J Tongariki (α 115 Ala → Asp) was found in a Kilenge village in New Britain. Heterozygotes had 45 to 50 percent of the Hb J component (determined by cellulose acetate electrophoresis). Two homozygotes for Hb J had no Hb A, suggesting that in this family only one Hb$_{\alpha}$ structural locus is present.

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