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Liver Mitochondria from Manganese-Deficient and Pallid Mice: Function and Ultrastructure
Lucille S. Hurley, Linda L. Theriault and Ivor E. Dreosti
New Series, Vol. 170, No. 3964 (Dec. 18, 1970), pp. 1316-1318
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1730514
Page Count: 3
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Oxidative phosphorylation was studied in isolated liver mitochondria from manganese-deficient mice and in those from a mutant strain, pallid. In mitochondria from manganese-deficient mice, ratios of adenosine triphosphate formed to oxygen consumed were normal, but oxygen uptake was reduced. Electron microscopy of these mitochondria revealed ultrastructural abnormalities including elongation and reorientation of cristae. No biochemical or structural abnormalities were found in mitochondria from pallid mice.
Science © 1970 American Association for the Advancement of Science