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Journal Article

Narcotic Tolerance and Dependence: Lack of Relationship with Serotonin Turnover in the Brain

D. L. Cheney, A. Goldstein, S. Algeri and E. Costa
Science
New Series, Vol. 171, No. 3976 (Mar. 19, 1971), pp. 1169-1170
Stable URL: http://www.jstor.org/stable/1730617
Page Count: 2
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Abstract

Serotonin turnover was measured in mouse brain by means of the conversion of radioactivity from labeled tryptophan into serotonin. Animals with a high degree of tolerance to and physical dependence on morphine did not differ from control mice.

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