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Complete Amino Acid Sequence of the Mu Heavy Chain of a Human IgM Immunoglobulin

F. W. Putnam, G. Florent, C. Paul, T. Shinoda and A. Shimizu
Science
New Series, Vol. 182, No. 4109 (Oct. 19, 1973), pp. 287-291
Stable URL: http://www.jstor.org/stable/1737121
Page Count: 5
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Complete Amino Acid Sequence of the Mu Heavy Chain of a Human IgM Immunoglobulin
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Abstract

The amino acid sequence of the μ chain of a human IgM immunoglobulin, including the location of all disulfide bridges and oligosaccharides, has been determined. The homology of the constant regions of immunoglobulin μ, γ, α, and ε heavy chains reveals evolutionary relationships and suggests that two genes code for each heavy chain.

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