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Avian Muscular Dystrophy: Functional and Biochemical Improvement with Diphenylhydantoin
Richard K. Entrikin, Karen L. Swanson, Paul M. Weidoff, Gary T. Patterson and Barry W. Wilson
New Series, Vol. 195, No. 4281 (Mar. 4, 1977), pp. 873-875
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1743340
Page Count: 3
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Chicks affected with hereditary muscular dystrophy were injected twice daily with 20 milligrams of diphenylhydantoin per kilogram of body weight on days 1 to 40 after hatching. The righting ability of dystrophic chicks treated with diphenyl-hydantoin was improved compared to that of untreated dystrophic chicks, and acetylcholinesterase activity was reduced to normal levels in the posterior latissimus dorsi muscles.
Science © 1977 American Association for the Advancement of Science