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Surgical Removal of Adipose Tissue Alters Feeding Behavior and the Development of Obesity in Rats
Irving M. Faust, Patricia R. Johnson and Jules Hirsch
New Series, Vol. 197, No. 4301 (Jul. 22, 1977), pp. 393-396
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1744355
Page Count: 4
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Lipectomized and sham-operated rats were fed a high-fat diet to induce hyperphagia and rapid fat accumulation. Lipectomized rats with 25 percent fewer adipocytes were less hyperphagic and accumulated less fat, but their adipocytes remained equal in size to adipocytes of controls. A role for adipocyte size in fat storage regulation and food intake control is postulated.
Science © 1977 American Association for the Advancement of Science