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Manufactured Hexaparental Mice Show That Adults Are Derived from Three Embryonic Cells
Clement L. Markert and Robert M. Petters
New Series, Vol. 202, No. 4363 (Oct. 6, 1978), pp. 56-58
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1746110
Page Count: 3
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Two female chimeric mice have been produced by aggregates of three genetically marked eight-cell embryos. All three embryonic genotypes are clearly expressed in the pigment pattern of the adults. These hexaparental mice together with their littermates demonstrate that, in the 64-celled blastocyst, at least three cells, and probably only three, are the source of all adult tissues.
Science © 1978 American Association for the Advancement of Science