Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

Trisodium Phosphonoformate, a New Antiviral Compound

E. Helgstrand, B. Eriksson, N. G. Johansson, B. Lannerö, A. Larsson, A. Misiorny, J. O. Norén, B. Sjöberg, K. Stenberg, G. Stening, S. Stridh, B. Öberg, S. Alenius and L. Philipson
Science
New Series, Vol. 201, No. 4358 (Sep. 1, 1978), pp. 819-821
Stable URL: http://www.jstor.org/stable/1746142
Page Count: 3
  • More info
  • Cite this Item
Trisodium Phosphonoformate, a New Antiviral Compound
Preview not available

Abstract

Trisodium phosphonoformate selectively inhibits cell-free DNA polymerase activity induced by herpesvirus. The new inhibitor has an antiviral effect on herpes simplex virus types 1 and 2, pseudorabies virus, and infectious bovine rhinotracheitis virus in cell culture. It has a good therapeutic activity against cutaneous herpes simplex virus infection in guinea pigs.

Page Thumbnails

  • Thumbnail: Page 
819
    819
  • Thumbnail: Page 
820
    820
  • Thumbnail: Page 
821
    821