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Isolated Retinas Synthesize Visual Pigments from Retinol Congeners Delivered by Liposomes

S. Yoshikami and G. N. Nöll
Science
New Series, Vol. 200, No. 4348 (Jun. 23, 1978), pp. 1393-1395
Stable URL: http://www.jstor.org/stable/1746741
Page Count: 3
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Isolated Retinas Synthesize Visual Pigments from Retinol Congeners Delivered by Liposomes
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Abstract

Isolated vertebrate retinas bathed in circulating Ringer solution cannot regenerate all of their bleached visual pigments. When dioleoyl-lecithin vesicles containing certain retinol congeners are added to the Ringer solution, such retinas begin to regenerate pigment immediately. The visual pigment of a bleached perfused retina can now be restored fully, making the isolated retina an independent unit for study. Liposomes can protect oxygen-sensitive, lipid-soluble substances and deliver them to living cells.

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