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Modified Bases Characterized in Intact DNA by Mass-Analyzed Ion Kinetic Energy Spectrometry
A. E. Schoen, R. G. Cooks and J. L. Wiebers
New Series, Vol. 203, No. 4386 (Mar. 23, 1979), pp. 1249-1251
Published by: American Association for the Advancement of Science
Stable URL: http://www.jstor.org/stable/1747251
Page Count: 3
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Pyrolysis of DNA into a chemical ionization source yields protonated bases and other base-containing ions. Kinetic energy spectra allow the characterization of the bases 5-methylcytosine and 1-methyladenine from underivatized salmon sperm DNA. Isomeric bases are distinguishable with this technique.
Science © 1979 American Association for the Advancement of Science