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Journal Article

Human Skin Fibroblasts Derived from Papillary and Reticular Dermis: Differences in Growth Potential in vitro

Robert A. Harper and Gary Grove
Science
New Series, Vol. 204, No. 4392 (May 4, 1979), pp. 526-527
Stable URL: http://www.jstor.org/stable/1748818
Page Count: 2

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Topics: Papillae, Dermis, Cell lines, Skin, Fibroblasts, Abdomen, Cultured cells, Geographic regions, Thigh, Biopsies
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Abstract

Papillary fibroblasts, when compared to reticular fibroblasts from the same skin specimen, exhibit greater proliferative capacities in vitro. These results demonstrate a difference in function between morphologically similar cells obtained from the same tissue. Such findings represent an important consideration in the study of cell aging in vitro.

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