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Complex Mammary Carcinoma in a Tiger (Panthera tigris)

Zdenek Hruban, W. Ellis Carter, Thomas Meehan, Peregrine Wolff, Wilbur A. Franklin and Seymour Glagov
The Journal of Zoo Animal Medicine
Vol. 19, No. 4 (Dec., 1988), pp. 226-230
DOI: 10.2307/20094893
Stable URL: http://www.jstor.org/stable/20094893
Page Count: 5
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Complex Mammary Carcinoma in a Tiger (Panthera tigris)
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Abstract

An adult female tiger (Panthera tigris) was euthanized for a widely metastatic complex mammary carcinoma. Gross metastases were found in the lungs, liver, spleen, diaphragm, adrenals, and in regional, thoracic, and abdominal lymph nodes. Microscopic metastases were found in ovaries, wall of the uterus, pancreas, a renal glomerulus, and periaortic lymphatics. The tumor consisted of myoepithelial cells and adenocarcinomatous cells with squamous metaplasia. The metastases showed regional predominance of distinct cytological patterns. Uterine mucosal hyperplasia was probably the result of progestagens administered for estrus control.

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