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Insulin Sensitivity And Vascular Disease In Maturity-Onset Diabetics

A. E. Stocks and F. I. R. Martin
The British Medical Journal
Vol. 4, No. 5680 (Nov. 15, 1969), pp. 397-399
Published by: BMJ
Stable URL: http://www.jstor.org/stable/20378430
Page Count: 3
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Insulin Sensitivity And Vascular Disease In Maturity-Onset Diabetics
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Abstract

In 27 maturity-onset diabetics of more than 10 years' duration there was a significant tendency for both atherosclerosis and microangiopathy to be associated with a reduction in the acute hypoglycaemic effect of intravenous beef insulin. This finding is identical to that in a group of 51 insulin-dependent diabetics previously reported. It is suggested that insulin insensitivity probably precedes the appearance of vascular disease in diabetes and may be implicated in its production.

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