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Effect Of Controlled Oxygen Therapy On Arterial Blood Gases In Acute Respiratory Failure

D. A. Warrell, R. H. T. Edwards, S. Godfrey and N. L. Jones
The British Medical Journal
Vol. 2, No. 5707 (May 23, 1970), pp. 452-455
Published by: BMJ
Stable URL: http://www.jstor.org/stable/20383814
Page Count: 4
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Effect Of Controlled Oxygen Therapy On Arterial Blood Gases In Acute Respiratory Failure
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Abstract

Seven patients in acute exacerbation of chronic respiratory failure were given 24.5% and later 28% oxygen through Ventimasks. The mean increases in arterial PO₂ were 11 and 21 mm. Hg while breathing 24.5% and 28% oxygen respectively compared with control values while breathing air. Associated increases in arterial PCO₂ were 4 and 8 mm. Hg, respectively. In five of the patients these increases in inspired oxygen concentration resulted in useful increases in tissue oxygen supply without significant deterioration in ventilation, but in two patients arterial PCO₂ rose excessively and artificial ventilation was required.

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