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Relation Between Airways Obstruction And Co₂ Tension In Chronic Obstructive Airways Disease

D. J. Lane, J. B. L. Howell and B. Giblin
The British Medical Journal
Vol. 3, No. 5620 (Sep. 21, 1968), pp. 707-709
Published by: BMJ
Stable URL: http://www.jstor.org/stable/20394088
Page Count: 3
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Relation Between Airways Obstruction And Co₂ Tension In Chronic Obstructive Airways Disease
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Abstract

The relationship between the F.E.V.₁ as an index of airways obstruction and Pco₂ as an index of hypoventilation was investigated in 13 patients with chronic obstructive airways disease. Patients who had a normal Pco₂ despite severe airways obstruction retained relatively normal sensitivity to CO₂ as assessed by their "inspiratory mechanical work rate" response to CO₂. Others showed a raised Pco₂ in the presence of lesser degrees of airways obstruction and had reduced sensitivity to CO₂.

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