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Extra-Articular Features In Early Rheumatoid Disease

A. Fleming, Sally Dodman, June M. Crown and Mary Corbett
The British Medical Journal
Vol. 1, No. 6020 (May 22, 1976), pp. 1241-1243
Published by: BMJ
Stable URL: http://www.jstor.org/stable/20409902
Page Count: 3
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Extra-Articular Features In Early Rheumatoid Disease
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Abstract

One hundred and two patients who presented with rheumatoid disease within the first year of onset were studied prospectively every four months for a mean 4.5 years to assess the incidence of extra-articular features. The features that seemed to be common in the early stages included hand-muscle wasting, carpal tunnel syndrome, lymphadenopathy, non-specific ankle swelling, and rheumatoid nodules, and to a lesser extent hepatomegaly, being underweight, conjunctivitis, skin transparency, and a palpable thyroid gland. Those features which seldom occurred early included scleromalacia, temporal artery involvement, salivary gland enlargement, distal-motor neuropathy, splenomegaly, digital vasculitis, and pulmonary and cardiac complications. Being underweight indicated a significantly more severe outcome.

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