Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If You Use a Screen Reader

This content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.

Separation, Sickness, and Depression: A New Perspective on an Old Animal Model

Michael B. Hennessy, Patricia A. Schiml-Webb and Terrence Deak
Current Directions in Psychological Science
Vol. 18, No. 4 (August 2009), pp. 227-231
Stable URL: http://www.jstor.org/stable/20696036
Page Count: 5
  • Read Online (Free)
  • Subscribe ($19.50)
  • Cite this Item
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Separation, Sickness, and Depression: A New Perspective on an Old Animal Model
Preview not available

Abstract

Studies of prolonged separation from the attachment figure that were conducted with infant monkeys during the middle of the 20th century identified a passive behavioral response, termed "despair," that appeared to model human depressive illness. Studies in guinea pigs, which exhibit filial attachment that resembles attachment in monkeys, have described a similar passive response to briefer periods of maternal separation. Recent evidence indicates that elements of the immune system mediate the passive behavioral response of guinea pigs. These findings accord well with current ideas that immune responses contribute to depressive illness, suggest new hypotheses about how maternal separation might promote depression, and give us a rodent model in which such hypotheses might be tested.

Page Thumbnails

  • Thumbnail: Page 
227
    227
  • Thumbnail: Page 
228
    228
  • Thumbnail: Page 
229
    229
  • Thumbnail: Page 
230
    230
  • Thumbnail: Page 
231
    231