Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If You Use a Screen Reader

This content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.

The Small Subunit of Transcription Factor IIF Recruits RNA Polymerase II Into the Preinitiation Complex

Osvaldo Flores, Hua Lu, Marie Killeen, Jack Greenblatt, Zachary F. Burton and Danny Reinberg
Proceedings of the National Academy of Sciences of the United States of America
Vol. 88, No. 22 (Nov. 15, 1991), pp. 9999-10003
Stable URL: http://www.jstor.org/stable/2358173
Page Count: 5
  • Read Online (Free)
  • Subscribe ($19.50)
  • Cite this Item
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
The Small Subunit of Transcription Factor IIF Recruits RNA Polymerase II Into the Preinitiation Complex
Preview not available

Abstract

We found that transcription factor IIF mediates the association of RNA polymerase II with promoter sequences containing transcription factors IID, IIB, and IIA (DAB complex). The resulting DNA-protein complex contained RNA polymerase II and the two subunits of transcription factor IIF (RAP 30 and RAP 74). Cloned human RAP 30 was sufficient for the recruitment of RNA polymerase II to the DAB complex. This ability of RAP 30 to recruit RNA polymerase to a promoter is also a characteristic of σ factors in prokaryotes.

Page Thumbnails

  • Thumbnail: Page 
9999
    9999
  • Thumbnail: Page 
10000
    10000
  • Thumbnail: Page 
10001
    10001
  • Thumbnail: Page 
10002
    10002
  • Thumbnail: Page 
10003
    10003