You are not currently logged in.
Access JSTOR through your library or other institution:
If You Use a Screen ReaderThis content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
The Chemistry of Phyletic Dominance
Jerrold Meinwald and Thomas Eisner
Proceedings of the National Academy of Sciences of the United States of America
Vol. 92, No. 1 (Jan. 3, 1995), pp. 14-18
Published by: National Academy of Sciences
Stable URL: http://www.jstor.org/stable/2366491
Page Count: 5
You can always find the topics here!Topics: Arthropods, Alkaloids, Chemicals, Beetles, Spiders, Insect larvae, Biochemistry, Animals, Venoms, Fatty acids
Were these topics helpful?See something inaccurate? Let us know!
Select the topics that are inaccurate.
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Preview not available
Studies of arthropod defensive chemistry continue to bring to light novel structures and unanticipated biosynthetic capabilities. Insect alkaloids, such as the heptacyclic acetogenin chilocorine and the azamacrolides, exemplify both of these aspects of arthropod chemistry. Spider venoms are proving to be rich sources of neuroactive components of potential medical interest. The venom of a fishing spider, Dolomedes okefinokensis, has yielded a polyamine which reversibly blocks L- and R-type voltage-sensitive calcium channels. Most recently, we have characterized, from the funnel-web spider Hololena curta, a sulfated nucleoside glycoside which serves as a reversible blocker of glutamate-sensitive calcium channels. The ability to synthesize or acquire an extremely diverse array of compounds for defense, offense, and communication appears to have contributed significantly to the dominant position that insects and other arthropods have attained.
Proceedings of the National Academy of Sciences of the United States of America © 1995 National Academy of Sciences