You are not currently logged in.
Access JSTOR through your library or other institution:
If You Use a Screen ReaderThis content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
The Manifestation of Phenotypic Selection at Constituent Loci. I. Stabilizing Selection
R. B. Campbell
Vol. 38, No. 5 (Sep., 1984), pp. 1033-1038
Published by: Society for the Study of Evolution
Stable URL: http://www.jstor.org/stable/2408437
Page Count: 6
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Preview not available
The effect of stabilizing phenotypic selection on the dynamics of allele frequencies at loci which govern the selected trait is investigated. Centripetal selection which restores the phenotypic optimum 0 by multiplying the mean phenotype by (1 - Ch2) is employed. It is found that the population mean is maintained sufficiently near the optimum so that directional selection contributes less than random drift to the dynamics of allele frequencies at individual loci (i.e., all loci are near neutral). However, if the population is sufficiently large, disruptive selection against new mutations becomes significant with the result that the total heterozygosity of the population is bounded, independent of population size. The model employed is a generalization of the fitness function w(x) = e-ax2 with additive non-epistasis between loci. The infinite loci model, which provides that the set of loci which are segregating varies over time, is also employed.
Evolution © 1984 Society for the Study of Evolution