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Journal Article

Cutaneous wound healing: Significance of proteoglycans in scar formation

V. Prathiba and P. D. Gupta
Current Science
Vol. 78, No. 6 (25 March 2000), pp. 697-701
Stable URL: http://www.jstor.org/stable/24103884
Page Count: 5
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Cutaneous wound healing: Significance of proteoglycans in scar formation
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Abstract

Proteoglycans (PGs), components of extracellular matrix (ECM), play an important role in modulating the structure and regulating the functions of the skin. The timely turnover of PGs influence the development and differentiation of cells. Wound healing also depends on the level of PGs which if not adequate leads to abnormal scars. The role of PGs in different phases of wound healing and their implication in the formation of abnormal scars and several other skin disorders are discussed in the present review.

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